pganddrugresponse.blogspot.com
Pharmacogenetics and Variability in Drug Response: June 2009
http://pganddrugresponse.blogspot.com/2009_06_01_archive.html
8220;The things we hate about ourselves aren't more real than things we like about ourselves.” Ellen Goodman. Monday, June 15, 2009. The CYP4F2 is involved in the synthesis of a number of sterols and lipids. Because it was involved in the production of 20-hydroxyeicosatetraenoic acid (20-HETE), it was postulated to be involved in the pathophysiology of hypertension. It is now thought to be also involved in the. Breakdown of Vit K1. PharmacoGenetics and Variability in Drug Response. Edmund J.D. Lee. Pharm...
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Entries from October 2008 - Let's Get Personal - reagank.com
http://www.reagank.com/quicklinks/2008/10
Science, Policy, and Ethics in Personalized Medicine. Pharmacogenomics: The Promise of Personalized Medicine for CNS Disorders. It's very heartening to me to see the concept of individualized treatment move outside of cancer, but still everything I see says "promise", "prospect", or "needs to be done". Personalized vaccines: the emerging field of vaccinomics. 1) Vaccinomics might be one step over the "omics" line. 2) Never trust anyone who uses the term "golden age" in quotes. All of Reagan's Connotea pa...
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Welcome - Let's Get Personal! - Let's Get Personal - reagank.com
http://www.reagank.com/2007/03/welcome_lets_get_personal.php
Science, Policy, and Ethics in Personalized Medicine. What is Personalized Medicine? Welcome - Let's Get Personal! After a long time of thinking about it (and a long time spent procrastinating), I've decided to resurrect the blog. So I've slapped on a new coat of paint, added a few new gew-gaws, and I'm off to the races. Reagank 1:11 PM 03/01/2007. March 1, 2007 2:15 PM. Came here via Tangled Bank. Glad I found you! We can always use more genetics bloggers. :) Best of luck on the thesis. Laparoscopic Gas...
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Reagan's Curriculum Vitae - Let's Get Personal - reagank.com
http://www.reagank.com/cv.php
Science, Policy, and Ethics in Personalized Medicine. Address: 4790 Washtenaw Ave Apt. B3. Ann Arbor, MI 48108. 1997-2001 Rochester Institute of Technology, B.S. Biology. 2003-2006 University of Michigan, M.S., Bioinformatics. 2003-2005 University of Michigan, Ph.D. Pre-Candidate, Bioinformatics. 2005-Present University of Michigan, Ph.D. Candidate, Bioinformatics. Developing flexible and integrative risk prediction systems for use in personalized medicine. Jan 2004 - Apr. 2004, Graduate Student, Uni...
pganddrugresponse.blogspot.com
Pharmacogenetics and Variability in Drug Response: November 2011
http://pganddrugresponse.blogspot.com/2011_11_01_archive.html
8220;The things we hate about ourselves aren't more real than things we like about ourselves.” Ellen Goodman. Sunday, November 20, 2011. The latest plot of numbers of publications suing the terms 'Pharmacogenetics', 'Pharmacogenomics', and 'Personalized Medicine'. (see previous plot). Perhaps P'genomics should be considered a subset of P'genetics rather than what has often conversely been suggested. PharmacoGenetics and Variability in Drug Response. Friday, November 18, 2011. Blood-brain barrier (BBB), f...
pganddrugresponse.blogspot.com
Pharmacogenetics and Variability in Drug Response: The issue of clarithromycin and increased cardiac deaths
http://pganddrugresponse.blogspot.com/2014/08/the-issue-of-clarithromycin-and.html
8220;The things we hate about ourselves aren't more real than things we like about ourselves.” Ellen Goodman. Friday, August 22, 2014. The issue of clarithromycin and increased cardiac deaths. Just this last week I was discussing with my students, the various factors contributing to variable drug response. And possible differences in the risk-benefit ratios for the same drug in different individuals. The recent publicity about increased cardiac death risks associated with clarithromycin. Pharmacogenetics...
pganddrugresponse.blogspot.com
Pharmacogenetics and Variability in Drug Response: October 2011
http://pganddrugresponse.blogspot.com/2011_10_01_archive.html
8220;The things we hate about ourselves aren't more real than things we like about ourselves.” Ellen Goodman. Friday, October 21, 2011. Stress - Nature vs Nurture: Lessons for drug response variability. This has been abstracted from Darlene Francis and Daniela Kaufer's essay in Reading Frames: The Scientist October 2011. Scientists and laymen alike still spend too much time and effort trying to quantify the relative importance of nature and nurture. PharmacoGenetics and Variability in Drug Response.
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The Genetic Information Nondiscrimination Act of 2007 - Let's Get Personal - reagank.com
http://www.reagank.com/2007/03/the_genetic_information_nondis.php
Science, Policy, and Ethics in Personalized Medicine. Realizing the Promise of Pharmacogeomics. The Genetic Information Nondiscrimination Act of 2007. I'm going to deviate a little from the planned topic for today. A bill I've mentioned before. The Genetic Information Nondiscrimination Act. Has been in the news. Recently, and will hopefully pass within the next few weeks. I have a ton of respect for Congresswoman Slaughter. The bill begins with five findings that motivate the bill and inform its purpose:.
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Entries in ethics - Let's Get Personal - reagank.com
http://www.reagank.com/ethics
Science, Policy, and Ethics in Personalized Medicine. What are the Ethical Issues in Personalized Medicine? I've discussed some of the scientific. Becuase these issues are so much more difficult, I'm going to limit myself to three different classes of issues:. Allowing access to personalized medicine. Does it cover a person's genetic makeup? For example, if a person has this information collected for use in risk profiling or diagnosis, should that then automatically commit them to allowing their data to ...
pganddrugresponse.blogspot.com
Pharmacogenetics and Variability in Drug Response: October 2010
http://pganddrugresponse.blogspot.com/2010_10_01_archive.html
8220;The things we hate about ourselves aren't more real than things we like about ourselves.” Ellen Goodman. Sunday, October 31, 2010. Many people agonize about the predictivity of the science of pharmacogenetics. Somehow there is an expectation that pharmacogenetics should somehow lead to position where we can stop thinking. Sounds a bit harsh but true. Pharmacogenetics began as a science. Or HLA B*1502 for carbamazepine-SJS. FDA classification: , for information only; , recommended; , required. This l...
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