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Michael James' Lab

Message from Dr. James. My laboratory focuses on three major projects. We are making great progress in understanding lysine biosynthesis in plants. Both involve structures of enzymes derived from Arabidopsis thaliana, DAP aminotransferase and DAP epimerase. The former is an enzyme also found in Chlamidia and we are working on the structure of this enzyme as well. We have obtained crystals of an ScFv that recognizes an epitope on the prion protein. For questions or comments.

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Michael James' Lab | xray.biochem.ualberta.ca Reviews
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Message from Dr. James. My laboratory focuses on three major projects. We are making great progress in understanding lysine biosynthesis in plants. Both involve structures of enzymes derived from Arabidopsis thaliana, DAP aminotransferase and DAP epimerase. The former is an enzyme also found in Chlamidia and we are working on the structure of this enzyme as well. We have obtained crystals of an ScFv that recognizes an epitope on the prion protein. For questions or comments.
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Michael James' Lab | xray.biochem.ualberta.ca Reviews

https://xray.biochem.ualberta.ca

Message from Dr. James. My laboratory focuses on three major projects. We are making great progress in understanding lysine biosynthesis in plants. Both involve structures of enzymes derived from Arabidopsis thaliana, DAP aminotransferase and DAP epimerase. The former is an enzyme also found in Chlamidia and we are working on the structure of this enzyme as well. We have obtained crystals of an ScFv that recognizes an epitope on the prion protein. For questions or comments.

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Michael James' Lab

http://xray.biochem.ualberta.ca/mjl/people.html

Technicians and Support Staff. For questions or comments.

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Michael James' Lab

http://xray.biochem.ualberta.ca/mjl/what_we_do.html

The major findings in our work on viral enzymes are associated with discovering how the proteinases and the polymerases work. With this critical knowledge, the design of more effective inhibitors that can be developed into antiviral compounds will be assisted. For example, our work with ViroChem Pharma Inc. has led to several compounds to treat HCVthat are in clinical trials. The structure of the arginine co-repressor, Rv1657, bound to a 16 base-pair segment of DNA with the operator sequence, has the pro...

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Michael James' Lab

http://xray.biochem.ualberta.ca/mjl/publications.html

For questions or comments.

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Michael James' Lab

http://xray.biochem.ualberta.ca/mjl/links.html

SickKids: the Lysosomal Storage Research Group. Previous version of James' lab web-site. For questions or comments.

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Message from Dr. James. My laboratory focuses on three major projects. We are making great progress in understanding lysine biosynthesis in plants. Both involve structures of enzymes derived from Arabidopsis thaliana, DAP aminotransferase and DAP epimerase. The former is an enzyme also found in Chlamidia and we are working on the structure of this enzyme as well. We have obtained crystals of an ScFv that recognizes an epitope on the prion protein. For questions or comments.

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