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Our laboratory studies the cellular surveillance and repair network for double-strand break DNA damage as well as the pathway that targets nonsense mRNAs for degradation. We are using a combination of experimental systems and approaches to decipher the molecular mechanisms that control these pathways and to identify potential crosstalk between DNA and RNA surveillance systems, with the ultimate goal of identifying novel cancer therapeutic strategies. Department of Cell Biology and Physiology.

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Our laboratory studies the cellular surveillance and repair network for double-strand break DNA damage as well as the pathway that targets nonsense mRNAs for degradation. We are using a combination of experimental systems and approaches to decipher the molecular mechanisms that control these pathways and to identify potential crosstalk between DNA and RNA surveillance systems, with the ultimate goal of identifying novel cancer therapeutic strategies. Department of Cell Biology and Physiology.
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https://youlab.wustl.edu

Our laboratory studies the cellular surveillance and repair network for double-strand break DNA damage as well as the pathway that targets nonsense mRNAs for degradation. We are using a combination of experimental systems and approaches to decipher the molecular mechanisms that control these pathways and to identify potential crosstalk between DNA and RNA surveillance systems, with the ultimate goal of identifying novel cancer therapeutic strategies. Department of Cell Biology and Physiology.

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ICCE Institute | Members, Associates, Affiliates | Washington University School of Medicine

http://www.icce-wustl.org/lab-members.html

Members, Associates, Affiliates. Members, Associates, Affiliates. Members, Associates, Affiliates. Greg Longmore, M.D. Director of ICCE Institute. Professor of Medicine and Cell Biology and Physiology. Milan G. Chheda, M.D. Assistant Professor of Medicine and Neurology. David DeNardo Ph.D. Assistant Professor of Medicine and Pathology and Immunology. Vijay Sharma Ph.D. Associate Professor of Radiology and Biomedical Engineering. Sheila Stewart, Ph.D. Jason Weber, Ph.D. Audrey Brenot, Ph.D. Associate Prof...

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youlab.wustl.edu youlab.wustl.edu

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Our laboratory studies the cellular surveillance and repair network for double-strand break DNA damage as well as the pathway that targets nonsense mRNAs for degradation. We are using a combination of experimental systems and approaches to decipher the molecular mechanisms that control these pathways and to identify potential crosstalk between DNA and RNA surveillance systems, with the ultimate goal of identifying novel cancer therapeutic strategies. Department of Cell Biology and Physiology.

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