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CaMPDB : Calpain for Modulatory Proteolysis

Welcome to CaMPDB, Calpain for Modulatory Proteolysis Database. Try CalCleave, our online cleavage site predictor ». 1496 calpain sequences ( CL. 2018 calpain substrate sequences. 104 curated sequences ( SB. 1914 expanded sequences ( XSB. 209 calpastatin sequences ( CT. Total : 3723 sequences ≫ More. D duVerle, I Takigawa, Y Ono, H Sorimachi, H Mamitsuka, CaMPDB: a Resource for Calpain and Modulatory Proteolysis, Genome Informatics. 22: 202-214 (2009) [ pubmed. Last modified: 2017-06-15 12:53:35 0900.

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CaMPDB : Calpain for Modulatory Proteolysis | calpain.org Reviews
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Welcome to CaMPDB, Calpain for Modulatory Proteolysis Database. Try CalCleave, our online cleavage site predictor ». 1496 calpain sequences ( CL. 2018 calpain substrate sequences. 104 curated sequences ( SB. 1914 expanded sequences ( XSB. 209 calpastatin sequences ( CT. Total : 3723 sequences ≫ More. D duVerle, I Takigawa, Y Ono, H Sorimachi, H Mamitsuka, CaMPDB: a Resource for Calpain and Modulatory Proteolysis, Genome Informatics. 22: 202-214 (2009) [ pubmed. Last modified: 2017-06-15 12:53:35 0900.
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2 substrates
3 calpastatin
4 campdb
5 data summary
6 reference
7 journal
8 download
9 feedback
10 links
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CaMPDB : Calpain for Modulatory Proteolysis | calpain.org Reviews

https://calpain.org

Welcome to CaMPDB, Calpain for Modulatory Proteolysis Database. Try CalCleave, our online cleavage site predictor ». 1496 calpain sequences ( CL. 2018 calpain substrate sequences. 104 curated sequences ( SB. 1914 expanded sequences ( XSB. 209 calpastatin sequences ( CT. Total : 3723 sequences ≫ More. D duVerle, I Takigawa, Y Ono, H Sorimachi, H Mamitsuka, CaMPDB: a Resource for Calpain and Modulatory Proteolysis, Genome Informatics. 22: 202-214 (2009) [ pubmed. Last modified: 2017-06-15 12:53:35 0900.

INTERNAL PAGES

calpain.org calpain.org
1

CaMPDB :: Substrate :: Overview

http://calpain.org/overview.rb?cls=substrate

Calpain (EC 3.4.22.17, Clan CA, family C02) has a substrate specificity that is relatively restricted, and most of oligopeptides are not efficiently hydrolyzed. Casein is the most popular substrate for. At 30oC for 20 min, the acid-soluble supernatant made by adding 0.5 ml of 10% trichloroacetic acid and centrifugation shows an increase of 0.333 absorbance unit at 280 nm). Activity is dependent on the Ca. 2004) Protein kinases, phosphatases, phospholipases, cytoskeletal proteins, membrane proteins, cytok...

2

CaMPDB :: Calpain :: Statistics

http://calpain.org/statistics.rb?cls=calpain

Sixteen calpain types of vertebrates and their reference sequences. NCBI Protein ID (CaMP ID). NP 005177 ( CL0892. NP 001739 ( CL0890. NP 000061 ( CL0842. NP 004046 ( CL0891. NP 055104 ( CL0904. NP 055111 ( CL0905. XP 943978 ( CL1417. NP 006606 ( CL0894. NP 075571 ( CL0913. NP 008989 ( CL0895. NP 653292 ( CL0946. NP 653176 ( CL0945. NP 005623 ( CL0893. NP 990634 ( CL0963. Number of sequences in 16 calpain types. Mus musculus (house mouse). Rattus norvegicus (Norway rat). Canis lupus familiaris (dog).

3

CaMPDB :: Substrate :: Predict

http://calpain.org/predict.rb?cls=substrate

Enter your query sequence in FASTA-style format:. SB0012 gi 119936491 gb ABM06136.1 H2B histone family, member L [Bos taurus] MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDI FERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK. DuVerle DA, Ono Y, Sorimachi H, Mamitsuka H, 2011 Calpain Cleavage Prediction Using Multiple Kernel Learning. PLoS ONE 6(5): e19035. More info ».

4

CaMPDB :: Substrate :: Statistics

http://calpain.org/statistics.rb?cls=substrate

Position Specific Scoring Matrix (SB). Frequency Counts Two-Sided Binomial Exact Test P-Values (SB). The procedure for computing each score. The above score of an amino acid at each position was computed by first dividing the occururence ratio of an amino acid to all amino acids by the composition ratio of this amino acid to all amino acids and then taking the logarithm of this. We used the following amino acid composition ratio from UniProtKB/Swiss-Prot protein knowledgebase release 53.3 statistics:.

5

CaMPDB :: About

http://calpain.org/index.rb?cls=about

Welcome to CaMPDB, Calpine for Modulatory Proteolysis Database. A unique, significant feature of this database is that one or more proteolytic sites of each substrate are collected from literature. Furthermore, systematic experiments on proteolysis of peptide fragments including these sites were conducted by our own, and resulting real values are stored in the substates part. David duVerle, Ichigaku Takigawa, Yasuko Ono, Hiroyuki Sorimachi, Hiroshi Mamitsuka. Genome Informatics 22: 202-214 (2009).

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ccd.biocuckoo.org ccd.biocuckoo.org

GPS-CCD 1.0 - Computational Predictioin of Calpain Cleavage Sites

http://ccd.biocuckoo.org/links.php

Last update: Feb. 28th, 2014. Computational resources of protein cleavage, etc. :. Last updated: Feb. 26th, 2011. Other resource of calpains and calpain-mediated cleavage. Predict the cleavage of substrates for proteinases including calpains( Verspurten,. A database on calpain, its substrates and calpastatin. A site-specific substrates prediction server was also provided.( duVerle,. Other resource of protein cleavage. Proteases and Protease-mediated cleavage. 2 Predict Putative Substrates of Proteases.

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Regulatory Elements of Marine Cyanobacteria

http://www.jsbi.org/pdfs/journal1/IBSB09/IBSB09017.html

CaMPDB: a Resource for Calpain and Modulatory Proteolysis. David duVerle [1](dave@kuicr.kyoto-u.ac.jp). Ichigaku Takigawa [1](takigawa@kuicr.kyoto-u.ac.jp). Yasuko Ono [2](ono-ys@igakuken.or.jp). Hiroyuki Sorimachi [2](sorimachi-hr@igakuken.or.jp). H Mamitsuka [1](mami@kuicr.kyoto-u.ac.jp). 1] Bioinformatics Center, Kyoto University, Gokasho, Uji 611-0011, Japan. 2] Calpain Project, Rinshoken, Tokyo 156-8506, Japan. Japanese Society for Bioinformatics.

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Calpain Research Portal: Calpain Structure and Nomenclature

Welcome to Calpain Research Portal! Calpain is an intracellular Ca. Dependent cysteine protease (EC 3.4.22.17; Clan CA, family C02). Calpain has limited proteolytic activity; it transforms or modulates the structure and/or activity of its substrates. It is, therefore, referred to as a modulator protease . Calpains are found in almost all eukaryotes and a few eubacteria, but not in archaebacteria. In the human genome, 15 genes (. Encode a calpain-like protease ( CysPc. We very much welcome your comments!

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CaMPDB : Calpain for Modulatory Proteolysis

Welcome to CaMPDB, Calpain for Modulatory Proteolysis Database. Try CalCleave, our online cleavage site predictor ». 1496 calpain sequences ( CL. 2018 calpain substrate sequences. 104 curated sequences ( SB. 1914 expanded sequences ( XSB. 209 calpastatin sequences ( CT. Total : 3723 sequences ≫ More. D duVerle, I Takigawa, Y Ono, H Sorimachi, H Mamitsuka, CaMPDB: a Resource for Calpain and Modulatory Proteolysis, Genome Informatics. 22: 202-214 (2009) [ pubmed. Last modified: 2017-06-15 12:53:35 0900.

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